How Does a High DCIS Score Result Impact Your Breast Cancer Treatment?

How Does a High DCIS Score Result Impact Treatment Recommendations?

Breast cancer conceptThe Oncotype DX test is a diagnostic test developed to help breast cancer patients who have been recently diagnosed with DCIS (Ductal Carcinoma In Situ). What does it mean if you have a high DCIS score from the Oncotype DX Breast Cancer Assay? Is this a good thing or a bad thing?

First, you should know that for a DCIS Recurrence score to be considered high, it must be greater than 31.

If you have a high score, the cancer has a high risk of recurrence and the benefits of chemotherapy for early-stage breast cancer or radiation therapy for DCIS are likely to be greater than the risks.

Surgical Oncologist mentions that although the score was not intended to predict benefit from mastectomy, there are some women who make decisions about whether or not she wants a mastectomy based on the score.

Find out how exactly a high DCIS Score can impact your treatment recommendations.

Transcript

Jennifer B. Manders:  A high Oncotype DCIS score means that a woman’s likelihood of recurrence in that breast at 10 years or prior to 10 years is high enough that it warrants that she get treatment that would reduce her risk as much as possible. 

In those situations, the physicians would recommend that not only should she undergo a lumpectomy but also radiation therapy and if her cells are estrogen and progesterone receptor positive, then tamoxifen may also be of benefit. 

Although, the score was not intended to predict benefit from mastectomy, there are some women who make decisions about whether or not she wants a mastectomy based on the score meaning if the score is high enough and the risk for recurrence is high enough, a woman may decide she rather have mastectomy which is the most likely way she can reduce her own risk for in-breast recurrence at 10 years.